The film world gave a collective whimper of sadness last autumn, when it was reported that Ken Loach was at work on his last ever feature. The 77-year-old director seemed to confirm as much when he picked up a lifetime achievement award at the Berlin film festival in February, saying: "There comes a point when the spirit is willing but the flesh is maybe not so capable…"

Though Loach is still expected to work on documentaries, next month's Jimmy's Hall, a drama set in 1920s Ireland, recently selected to be in competition at Cannes, will be a swansong of sorts. To mark the occasion we've invited him to take part in our "You ask the questions" interview, in which Loach will get a grilling from you, the Observer's New Review readers.

Got a question you've always wanted to put to one of the greats of British cinema? Get in touch.

Perhaps you've been wondering just how much whiskey Loach sampled in preparation for his drama about Scottish distillers, The Angels' Share, released to great critical acclaim in 2012. Or how he found it directing Eric Cantona in his subtle 2009 comedy, Looking for Eric. Which of his 29 feature films is Loach asked about the most? Which does he like best? Which, if any, does he regret?

Loach has always been a great discoverer of acting talent, picking out the 14-year-old Dai Bradley for Kes (1970) and more recently Martin Compston in Sweet Sixteen (2002). What does he look out for when he's casting unknowns? And since 1964, and an early directorial gig on Z-Cars, the Nuneaton-born director has focused almost exclusively on British – and British working-class – subjects. Did his focus ever drift? Wasn't he ever tempted to go to Hollywood and make a film with explosions?

Ask anything you like: simply email review@observer.co.uk, tweet @ObsNewReview, get in touch via Facebook (facebook.com/ObserverNewReview) or post questions online. The deadline is midnight on Sunday, 27 April. Questions will be put to him for an article to be published in May.